Searchable abstracts of presentations at key conferences on calcified tissues

ba0006p125 | (1) | ICCBH2017

Identification and characterization of a novel microRNA inhibiting osteoblast functions by suppressing actin polymerization

John Aijaz Ahmad , Prakash Ravi , Singh Divya

MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as critical post-transcriptional regulators of gene expression. There is increasing evidence that miRNAs play an important role in osteoblast commitment and differentiation. The main aim of this study was to identify and characterize novel microRNAs regulating osteoblast functions. We report the role of mmu-miR-1187 in osteoblast differentiation and the mode by which it regulates osteogenesis. MicroRNA profiling of...